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Amyloid-Related Memory Decline in Preclinical Alzheimer’s Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months

High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cognitively normal (CN) older adults. However, the relationship between these two biomarkers and cognitive decline is unclear. The aim of this study was to investigate the r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thai, Christine, Lim, Yen Ying, Villemagne, Victor L., Laws, Simon M., Ames, David, Ellis, Kathryn A., Rainey-Smith, Stephanie R., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Maruff, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592244/
https://ncbi.nlm.nih.gov/pubmed/26430784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139082
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