Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease

IMPORTANCE: Older age, high levels of β-amyloid (Aβ), and the presence of the apolipoprotein E (APOE) ε4 allele are risk factors for Alzheimer disease (AD). However, the extent to which increasing age, Aβ, and ε4 are associated with memory decline remains unclear, and the age at which memory decline...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Lim, Yen Ying, Kalinowski, Pawel, Pietrzak, Robert H., Laws, Simon M., Burnham, Samantha C., Ames, David, Villemagne, Victor L., Fowler, Christopher J., Rainey-Smith, Stephanie R., Martins, Ralph N., Rowe, Christopher C., Masters, Colin L., Maruff, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933393/
https://ncbi.nlm.nih.gov/pubmed/29356823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.4325
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