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Roles of Mitochondrial DNA Mutations in Stem Cell Ageing
Mitochondrial DNA (mtDNA) mutations accumulate in somatic stem cells during ageing and cause mitochondrial dysfunction. In this review, we summarize the studies that link mtDNA mutations to stem cell ageing. We discuss the age-related behaviours of the somatic mtDNA mutations in stem cell population...
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| Publicado en: | Genes (Basel) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924524/ https://ncbi.nlm.nih.gov/pubmed/29584704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9040182 |
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