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Quantification of mitochondrial DNA mutation load
Mitochondrial DNA (mtDNA) mutations are an important cause of genetic disease and have been proposed to play a role in the ageing process. Quantification of total mtDNA mutation load in ageing tissues is difficult as mutational events are rare in a background of wild-type molecules, and detection of...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752485/ https://ncbi.nlm.nih.gov/pubmed/19624578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00505.x |
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