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Roles of Mitochondrial DNA Mutations in Stem Cell Ageing

Mitochondrial DNA (mtDNA) mutations accumulate in somatic stem cells during ageing and cause mitochondrial dysfunction. In this review, we summarize the studies that link mtDNA mutations to stem cell ageing. We discuss the age-related behaviours of the somatic mtDNA mutations in stem cell population...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Su, Tianhong, Turnbull, Doug M., Greaves, Laura C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924524/
https://ncbi.nlm.nih.gov/pubmed/29584704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9040182
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