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The rise and rise of mitochondrial DNA mutations

How mitochondrial DNA mutations clonally expand in an individual cell is a question that has perplexed mitochondrial biologists for decades. A growing body of literature indicates that mitochondrial DNA mutations play a major role in ageing, metabolic diseases, neurodegenerative diseases, neuromuscu...

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Détails bibliographiques
Publié dans:Open Biol
Auteurs principaux: Lawless, Conor, Greaves, Laura, Reeve, Amy K., Turnbull, Doug M., Vincent, Amy E.
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276526/
https://ncbi.nlm.nih.gov/pubmed/32428418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200061
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