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Human stem cell aging: do mitochondrial DNA mutations have a causal role?
A decline in the replicative and regenerative capacity of adult stem cell populations is a major contributor to the aging process. Mitochondrial DNA (mtDNA) mutations clonally expand with age in human stem cell compartments including the colon, small intestine, and stomach, and result in respiratory...
Sparad:
| I publikationen: | Aging Cell |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BlackWell Publishing Ltd
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331785/ https://ncbi.nlm.nih.gov/pubmed/24382254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12199 |
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