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Human stem cell aging: do mitochondrial DNA mutations have a causal role?
A decline in the replicative and regenerative capacity of adult stem cell populations is a major contributor to the aging process. Mitochondrial DNA (mtDNA) mutations clonally expand with age in human stem cell compartments including the colon, small intestine, and stomach, and result in respiratory...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331785/ https://ncbi.nlm.nih.gov/pubmed/24382254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12199 |
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