Ari-1 regulates myonuclear organization together with Parkin and is associated with aortic aneurysms

Nuclei are actively positioned and anchored to the cytoskeleton via the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex. We identified mutations in the Parkin-like E3 ubiquitin ligase Ariadne-1 (Ari-1) that affect the localization and distribution of LINC complex members in Drosophila. ari-...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Dev Cell
Huvudupphovsmän: Tan, Kai Li, Haelterman, Nele A., Kwartler, Callie S., Regalado, Ellen S., Lee, Pei-Tseng, Nagarkar-Jaiswal, Sonal, Guo, Dong-chuan, Duraine, Lita, Wangler, Michael F., Bamshad, Michael J., Nickerson, Deborah A., Lin, Guang, Milewicz, Dianna M., Bellen, Hugo J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920516/
https://ncbi.nlm.nih.gov/pubmed/29689197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.03.020
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk