Successes and Challenges of Using Whole Exome Sequencing to Identify Novel Genes Underlying an Inherited Predisposition for Thoracic Aortic Aneurysms and Acute Aortic Dissections

Thoracic aortic aneurysms involving the aortic root and/or ascending aorta can lead to acute aortic dissections. Approximately 20% of patients with thoracic aortic aneurysms and dissections (TAAD) have a family history of the disease, referred to as familial TAAD (FTAAD), which can be inherited in a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Milewicz, Dianna M., Regalado, Ellen, Shendure, Jay, Nickerson, Deborah A., Guo, Dongchuan
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917689/
https://ncbi.nlm.nih.gov/pubmed/23953976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2013.06.004
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares