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Successes and Challenges of Using Whole Exome Sequencing to Identify Novel Genes Underlying an Inherited Predisposition for Thoracic Aortic Aneurysms and Acute Aortic Dissections

Thoracic aortic aneurysms involving the aortic root and/or ascending aorta can lead to acute aortic dissections. Approximately 20% of patients with thoracic aortic aneurysms and dissections (TAAD) have a family history of the disease, referred to as familial TAAD (FTAAD), which can be inherited in a...

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書誌詳細
主要な著者: Milewicz, Dianna M., Regalado, Ellen, Shendure, Jay, Nickerson, Deborah A., Guo, Dongchuan
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917689/
https://ncbi.nlm.nih.gov/pubmed/23953976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2013.06.004
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