Ari-1 regulates myonuclear organization together with Parkin and is associated with aortic aneurysms

Nuclei are actively positioned and anchored to the cytoskeleton via the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex. We identified mutations in the Parkin-like E3 ubiquitin ligase Ariadne-1 (Ari-1) that affect the localization and distribution of LINC complex members in Drosophila. ari-...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Tan, Kai Li, Haelterman, Nele A., Kwartler, Callie S., Regalado, Ellen S., Lee, Pei-Tseng, Nagarkar-Jaiswal, Sonal, Guo, Dong-chuan, Duraine, Lita, Wangler, Michael F., Bamshad, Michael J., Nickerson, Deborah A., Lin, Guang, Milewicz, Dianna M., Bellen, Hugo J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920516/
https://ncbi.nlm.nih.gov/pubmed/29689197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.03.020
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