Treatment guidelines for thoracic aortic aneurysms and dissections based on the underlying causative gene

Por Milewicz, Dianna M., Regalado, Ellen S., Guo, Dong-chuan
Publicado em 2010

Exogenous Visual Orienting Is Associated with Specific Neurotransmitter Genetic Markers: A Population-Based Genetic Association Study

Por Lundwall, Rebecca A., Guo, Dong-Chuan, Dannemiller, James L.
Publicado em 2012

Acute Aortic Dissections with Pregnancy in Women with ACTA2 Mutations

Por Regalado, Ellen S., Guo, Dong-chuan, Estrera, Anthony L., Buja, L. Maximilian, Milewicz, Dianna M.
Publicado em 2013

Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2(+/−) mice

Por Cao, Jiumei, Gong, Limin, Guo, Dong-chuan, Mietzsch, Ulrike, Kuang, Shao-Qing, Kwartler, Callie S., Safi, Hazim, Estrera, Anthony, Gambello, Michael J., Milewicz, Dianna M.
Publicado em 2010

Influence of Host Interleukin-10 Polymorphisms on Development of Traveler's Diarrhea Due to Heat-Labile Enterotoxin-Producing Escherichia coli in Travelers from the United States W...

Por Flores, Jose, DuPont, Herbert L., Lee, Stephanie A., Belkind-Gerson, Jaime, Paredes, Mercedes, Mohamed, Jamal A., Armitige, Lisa Y., Guo, Dong-Chuan, Okhuysen, Pablo C.
Publicado em 2008

IL-6-STAT3 signaling mediates aortic dissections induced by angiotensin II via the Th17 lymphocyte-IL17 axis in C57BL/6 Mice

Por Ju, Xiaoxi, Ijaz, Talha, Sun, Hong, Ray, Sutapa, Lejeune, Wanda, Lee, Chang, Recinos, Adrian, Guo, Dong-Chuan, Milewicz, Dianna M., Tilton, Ronald G., Brasier, Allan R.
Publicado em 2013

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

Por Tieu, Brian C., Lee, Chang, Sun, Hong, LeJeune, Wanda, Recinos, Adrian, Ju, Xiaoxi, Spratt, Heidi, Guo, Dong-Chuan, Milewicz, Dianna, Tilton, Ronald G., Brasier, Allan R.
Publicado em 2009

Familial Thoracic Aortic Aneurysms and Dissections: Identification of a Novel Locus for Stable Aneurysms with a Low Risk for Progression to Aortic Dissection

Por Guo, Dong-Chuan, Regalado, Ellen S., Minn, Charles, Tran-Fadulu, Van, Coney, Joshua, Cao, Jiumei, Wang, Min, Yu, Robert K., Estrera, Anthony L., Safi, Hazim J., Shete, Sanjay S., Milewicz, Dianna M.
Publicado em 2010

Missense Mutations in FBN1 Exons 41 and 42 Cause Weill-Marchesani Syndrome with Thoracic Aortic Disease and Marfan Syndrome

Por Cecchi, Alana, Ogawa, Naomi, Martinez, Hugo R., Carlson, Alicia, Fan, Yuxin, Penny, Daniel J., Guo, Dong-chuan, Eisenberg, Steven, Safi, Hazim, Estrera, Anthony, Lewis, Richard A., Meyers, Deborah, Milewicz, Dianna M.
Publicado em 2013

Autosomal Dominant Inheritance of a Predisposition to Thoracic Aortic Aneurysms and Dissections and Intracranial Saccular Aneurysms

Por Regalado, Ellen, Medrek, Sarah, Tran-Fadulu, Van, Guo, Dong-Chuan, Pannu, Hariyadarshi, Golabbakhsh, Hossein, Smart, Suzanne, Chen, Julia H., Shete, Sanjay, Kim, Dong H., Stern, Ralph, Braverman, Alan C., Milewicz, Dianna M.
Publicado em 2011

Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms and sporadic aneurysms

Por He, Rumin, Guo, Dong-Chuan, Sun, Wei, Papke, Christina L., Duraisamy, Senthil, Estrera, Anthony L., Safi, Hazim J., Ahn, Chul, Buja, L. Maximilian, Arnett, Frank C., Zhang, Jingwu, Geng, Yong-Jian, Milewicz, Dianna M.
Publicado em 2008

Mutations in Myosin Light Chain Kinase Cause Familial Aortic Dissections

Por Wang, Li, Guo, Dong-chuan, Cao, Jiumei, Gong, Limin, Kamm, Kristine E., Regalado, Ellen, Li, Li, Shete, Sanjay, He, Wei-Qi, Zhu, Min-Sheng, Offermanns, Stephan, Gilchrist, Dawna, Elefteriades, John, Stull, James T., Milewicz, Dianna M.
Publicado em 2010

Mutations in Myosin Light Chain Kinase Cause Familial Aortic Dissections

Por Wang, Li, Guo, Dong-chuan, Cao, Jiumei, Gong, Limin, Kamm, Kristine E., Regalado, Ellen, Li, Li, Shete, Sanjay, He, Wei-Qi, Zhu, Min-Sheng, Offermanns, Stephan, Gilchrist, Dawna, Elefteriades, John, Stull, James T., Milewicz, Dianna M.
Publicado em 2011

Disrupted Nitric Oxide Signaling due to GUCY1A3 Mutations Increases Risk for Moyamoya Disease, Achalasia and Hypertension

Por Wallace, Stephanie, Guo, Dong-chuan, Regalado, Ellen, Mellor-Crummey, Lauren, Banshad, Michael, Nickerson, Deborah A., Dauser, Robert, Hanchard, Neil, Marom, Ronit, Martin, Emil, Berka, Vladimir, Sharina, Iraida, Ganesan, Vijeya, Saunders, Dawn, Morris, Shaine, Milewicz, Dianna M.
Publicado no Clin Genet (2016)

Rare Copy Number Variants Disrupt Genes Regulating Vascular Smooth Muscle Cell Adhesion and Contractility in Sporadic Thoracic Aortic Aneurysms and Dissections

Por Prakash, Siddharth K., LeMaire, Scott A., Guo, Dong-Chuan, Russell, Ludivine, Regalado, Ellen S., Golabbakhsh, Hossein, Johnson, Ralph J., Safi, Hazim J., Estrera, Anthony L., Coselli, Joseph S., Bray, Molly S., Leal, Suzanne M., Milewicz, Dianna M., Belmont, John W.
Publicado em 2010

Rare Copy Number Variants Disrupt Genes Regulating Vascular Smooth Muscle Cell Adhesion and Contractility in Sporadic Thoracic Aortic Aneurysms and Dissections

Por Prakash, Siddharth K., LeMaire, Scott A., Guo, Dong-Chuan, Russell, Ludivine, Regalado, Ellen S., Golabbakhsh, Hossein, Johnson, Ralph J., Safi, Hazim J., Estrera, Anthony L., Coselli, Joseph S., Bray, Molly S., Leal, Suzanne M., Milewicz, Dianna M., Belmont, John W.
Publicado em 2013

Exome Sequencing Identifies SMAD3 Mutations as a Cause of Familial Thoracic Aortic Aneurysm and Dissection with Intracranial and Other Arterial Aneurysms

Por Regalado, Ellen S., Guo, Dong-chuan, Villamizar, Carlos, Avidan, Nili, Gilchrist, Dawna, McGillivray, Barbara, Clarke, Lorne, Bernier, Francois, Santos-Cortez, Regie L., Leal, Suzanne M., Bertoli-Avella, Aida M., Shendure, Jay, Rieder, Mark J., Nickerson, Deborah A, Milewicz, Dianna M.
Publicado em 2011

Pathogenic FBN1 Variants in Familial Thoracic Aortic Aneurysms and Dissections

Por Regalado, Ellen S., Guo, Dong-chuan, Santos-Cortez, Regie Lyn P., Hostetler, Ellen, Bensend, Tracy A., Pannu, Hariyadarshi, Estrera, Anthony, Safi, Hazim, Mitchell, Anna L., Evans, James P., Leal, Suzanne M., Bamshad, Michael, Shendure, Jay, Nickerson, Deborah A., Milewicz, Dianna M.
Publicado no Clin Genet (2016)

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections

Por Guo, Dong-chuan, Grove, Megan L., Prakash, Siddharth K., Eriksson, Per, Hostetler, Ellen M., LeMaire, Scott A., Body, Simon C., Shalhub, Sherene, Estrera, Anthony L., Safi, Hazim J., Regalado, Ellen S., Zhou, Wei, Mathis, Michael R., Eagle, Kim A., Yang, Bo, Willer, Cristen J., Boerwinkle, Eric, Milewicz, Dianna M.
Publicado no Am J Hum Genet (2016)

Recurrent Chromosome 16p13.1 Duplications Are a Risk Factor for Aortic Dissections

Por Kuang, Shao-Qing, Guo, Dong-Chuan, Prakash, Siddharth K., McDonald, Merry-Lynn N., Johnson, Ralph J., Wang, Min, Regalado, Ellen S., Russell, Ludivine, Cao, Jiu-Mei, Kwartler, Callie, Fraivillig, Kurt, Coselli, Joseph S., Safi, Hazim J., Estrera, Anthony L., Leal, Suzanne M., LeMaire, Scott A., Belmont, John W., Milewicz, Dianna M.
Publicado em 2011