Mutations in Myosin Light Chain Kinase Cause Familial Aortic Dissections

Mutations in smooth muscle cell (SMC)-specific isoforms of α-actin and β-myosin heavy chain, two major components of the SMC contractile unit, cause familial thoracic aortic aneurysms leading to acute aortic dissections (FTAAD). To investigate whether mutations in the kinase that controls SMC contra...

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Detalhes bibliográficos
Main Authors: Wang, Li, Guo, Dong-chuan, Cao, Jiumei, Gong, Limin, Kamm, Kristine E., Regalado, Ellen, Li, Li, Shete, Sanjay, He, Wei-Qi, Zhu, Min-Sheng, Offermanns, Stephan, Gilchrist, Dawna, Elefteriades, John, Stull, James T., Milewicz, Dianna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978973/
https://ncbi.nlm.nih.gov/pubmed/21055718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.10.006
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