An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

Vascular inflammation contributes to cardiovascular diseases such as aortic aneurysm and dissection. However, the precise inflammatory pathways involved have not been clearly defined. We have shown here that subcutaneous infusion of Ang II, a vasopressor known to promote vascular inflammation, into...

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Bibliografiska uppgifter
Huvudupphovsmän: Tieu, Brian C., Lee, Chang, Sun, Hong, LeJeune, Wanda, Recinos, Adrian, Ju, Xiaoxi, Spratt, Heidi, Guo, Dong-Chuan, Milewicz, Dianna, Tilton, Ronald G., Brasier, Allan R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786788/
https://ncbi.nlm.nih.gov/pubmed/19920349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38308
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