A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic substances in cells. In a forward mosaic screen in Drosophila designed to identify genes required for neuronal function and...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Tian, Xuejun, Gala, Upasana, Zhang, Yongping, Shang, Weina, Nagarkar Jaiswal, Sonal, di Ronza, Alberto, Jaiswal, Manish, Yamamoto, Shinya, Sandoval, Hector, Duraine, Lita, Sardiello, Marco, Sillitoe, Roy V., Venkatachalam, Kartik, Fan, Hengyu, Bellen, Hugo J., Tong, Chao
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374850/
https://ncbi.nlm.nih.gov/pubmed/25811491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002103
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