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Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

The mammalian homotypic fusion and vacuole protein sorting (HOPS) complex is comprised of six subunits: VPS11, VPS16, VPS18, VPS39, VPS41 and the Sec1/Munc18 (SM) family member VPS33A. Human HOPS has been predicted to be a tethering complex required for fusion of intracellular compartments with lyso...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Wartosch, Lena, Günesdogan, Ufuk, Graham, Stephen C., Luzio, J. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons A/S 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510706/
https://ncbi.nlm.nih.gov/pubmed/25783203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12283
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