Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

The mammalian homotypic fusion and vacuole protein sorting (HOPS) complex is comprised of six subunits: VPS11, VPS16, VPS18, VPS39, VPS41 and the Sec1/Munc18 (SM) family member VPS33A. Human HOPS has been predicted to be a tethering complex required for fusion of intracellular compartments with lyso...

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Bibliographic Details
Published in:Traffic
Main Authors: Wartosch, Lena, Günesdogan, Ufuk, Graham, Stephen C., Luzio, J. Paul
Format: Artigo
Language:Inglês
Published: John Wiley & Sons A/S 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510706/
https://ncbi.nlm.nih.gov/pubmed/25783203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12283
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