HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development

Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells, in vitro, holds great promise for regenerative therapies. Primarily, this has been achieved in mouse cells by overexpression of the homeotic selector protein HOXB4. The exact cellular stage at which HOXB4 promotes hematopoiet...

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Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Teichweyde, Nadine, Kasperidus, Lara, Carotta, Sebastian, Kouskoff, Valerie, Lacaud, Georges, Horn, Peter A., Heinrichs, Stefan, Klump, Hannes
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919293/
https://ncbi.nlm.nih.gov/pubmed/29456178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.009
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