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HOXB4 Increases Runx1 Expression to Promote the de novo Formation of Multipotent Hematopoietic Cells

BACKGROUND: The de novo generation of patient-specific hematopoietic stem and progenitor cells from induced pluripotent stem cells (iPSCs) has become a promising approach for cell replacement therapies in the future. However, efficient differentiation protocols for producing fully functional human h...

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Detalles Bibliográficos
Publicado en:Transfus Med Hemother
Main Authors: Teichweyde, Nadine, Horn, Peter A., Klump, Hannes
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger GmbH 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473112/
https://ncbi.nlm.nih.gov/pubmed/28626363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000477130
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