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HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development

Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells, in vitro, holds great promise for regenerative therapies. Primarily, this has been achieved in mouse cells by overexpression of the homeotic selector protein HOXB4. The exact cellular stage at which HOXB4 promotes hematopoiet...

詳細記述

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書誌詳細
出版年:Stem Cell Reports
主要な著者: Teichweyde, Nadine, Kasperidus, Lara, Carotta, Sebastian, Kouskoff, Valerie, Lacaud, Georges, Horn, Peter A., Heinrichs, Stefan, Klump, Hannes
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919293/
https://ncbi.nlm.nih.gov/pubmed/29456178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.009
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