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HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development
Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells, in vitro, holds great promise for regenerative therapies. Primarily, this has been achieved in mouse cells by overexpression of the homeotic selector protein HOXB4. The exact cellular stage at which HOXB4 promotes hematopoiet...
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| Опубликовано в: : | Stem Cell Reports |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919293/ https://ncbi.nlm.nih.gov/pubmed/29456178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.009 |
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