TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

Protein arginine methyltransferase (PRMT) 4 (also known as coactivator-associated arginine methyltransferase 1; CARM1) is involved in a variety of biological processes and is considered as a candidate oncogene owing to its overexpression in several types of cancer. Selective PRMT4 inhibitors are use...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nakayama, Kazuhide, Szewczyk, Magdalena M., dela Sena, Carlo, Wu, Hong, Dong, Aiping, Zeng, Hong, Li, Fengling, de Freitas, Renato Ferreira, Eram, Mohammad S., Schapira, Matthieu, Baba, Yuji, Kunitomo, Mihoko, Cary, Douglas R., Tawada, Michiko, Ohashi, Akihiro, Imaeda, Yasuhiro, Saikatendu, Kumar Singh, Grimshaw, Charles E., Vedadi, Masoud, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Kiba, Atsushi, Tomita, Daisuke, Brown, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915086/
https://ncbi.nlm.nih.gov/pubmed/29719619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24883
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