Evaluation of a System-Specific Function To Describe the Pharmacokinetics of Benzylpenicillin in Term Neonates Undergoing Moderate Hypothermia

The pharmacokinetic (PK) properties of intravenous (i.v.) benzylpenicillin in term neonates undergoing moderate hypothermia after perinatal asphyxia were evaluated, as they have been unknown until now. A system-specific modeling approach was applied, in which our recently developed covariate model d...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Bijleveld, Yuma A., de Haan, Timo R., van der Lee, Johanna H., Groenendaal, Floris, Dijk, Peter H., van Heijst, Arno, de Jonge, Rogier C. J., Dijkman, Koen P., van Straaten, Henrica L. M., Rijken, Monique, Zonnenberg, Inge A., Cools, Filip, Zecic, Alexandra, Nuytemans, Debbie H. G. M., van Kaam, Anton H., Mathôt, Ron A. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914006/
https://ncbi.nlm.nih.gov/pubmed/29378710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02311-17
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