Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study

<p>Abstract</p> <p>Background</p> <p>In the Netherlands, perinatal asphyxia (severe perinatal oxygen shortage) necessitating newborn resuscitation occurs in at least 200 of the 180–185.000 newly born infants per year. International randomized controlled trials have demo...

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Autori principali: de Haan Timo R, Bijleveld Yuma A, van der Lee Johanna H, Groenendaal Floris, van den Broek Marcel PH, Rademaker Carin MA, van Straaten Henrica LM, van Weissenbruch Mirjam M, Vermeulen Jeroen R, Dijk Peter H, Dudink Jeroen, Rijken Monique, van Heijst Arno, Dijkman Koen P, Gavilanes Danilo, van Kaam Anton H, Offringa Martin, Mathôt Ron AA
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-05-01
Serie:BMC Pediatrics
Soggetti:
Perinatal asphyxia, Therapeutic hypothermia
Pharmacokinetic research
Drug monitoring
Evidence based
Drug dosing
Guideline
Accesso online:http://www.biomedcentral.com/1471-2431/12/45
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