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Autophagy is a major regulator of β-cell insulin homeostasis
AIMS/HYPOTHESIS: We studied the role of protein degradation pathways in the regulation of insulin production and secretion and hypothesized that autophagy regulates proinsulin degradation, thereby modulating β-cell function. METHODS: Proinsulin localization in autophagosomes was demonstrated by conf...
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| Publicado no: | Diabetologia |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912938/ https://ncbi.nlm.nih.gov/pubmed/26831301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3868-9 |
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