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Improvement of ER stress-induced diabetes by stimulating autophagy

Pancreatic β-cell dysfunction is central in diabetes. The diabetic milieu may impair proinsulin folding, leading to β-cell endoplasmic reticulum (ER) stress and apoptosis, and thus a worsening of the diabetes. Autophagy is crucial for the well-being of the β-cell; however, the impact of stimulating...

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Detalhes bibliográficos
Main Authors: Bachar-Wikstrom, Etty, Wikstrom, Jakob D., Kaiser, Nurit, Cerasi, Erol, Leibowitz, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627683/
https://ncbi.nlm.nih.gov/pubmed/23380813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23642
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