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Stimulation of Autophagy Improves Endoplasmic Reticulum Stress–Induced Diabetes
Accumulation of misfolded proinsulin in the β-cell leads to dysfunction induced by endoplasmic reticulum (ER) stress, with diabetes as a consequence. Autophagy helps cellular adaptation to stress via clearance of misfolded proteins and damaged organelles. We studied the effects of proinsulin misfold...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609555/ https://ncbi.nlm.nih.gov/pubmed/23274896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1474 |
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