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Regulation of kidney development by the Mdm2/Mdm4–p53 axis

While p53 activity is required for tumour suppression, unconstrained p53 activity on the other hand is detrimental to the organism, resulting in inappropriate cellular death or proliferation defects. Unimpeded p53 activity is lethal in the developing embryo, underlining the need for maintaining a ti...

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Detaylı Bibliyografya
Yayımlandı:J Mol Cell Biol
Asıl Yazarlar: El-Dahr, Samir, Hilliard, Sylvia, Saifudeen, Zubaida
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907835/
https://ncbi.nlm.nih.gov/pubmed/28096292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjx005
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