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Mdm4 controls ureteric bud branching via regulation of p53 activity
The antagonism between Mdm2 and its close homolog Mdm4 (also known as MdmX) and p53 is vital for embryogenesis and organogenesis. Previously, we demonstrated that targeted disruption of Mdm2 in the Hoxb7+ ureteric bud (Ub) lineage, which gives rise to the renal collecting system, causes renal hypody...
שמור ב:
| הוצא לאור ב: | Mech Dev |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7487065/ https://ncbi.nlm.nih.gov/pubmed/32464196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2020.103616 |
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