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The Mdm2-p53 pathway: multiple roles in kidney development

The molecular basis of nephron progenitor cell renewal and differentiation into nascent epithelial nephrons is an area of intense investigation. Defects in these early stages of nephrogenesis lead to renal hypoplasia, and eventually hypertension and chronic kidney disease. Terminal nephron different...

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Bibliografiske detaljer
Main Authors: El-Dahr, Samir S., Hilliard, Sylvia, Aboudehen, Karam, Saifudeen, Zubaida
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969418/
https://ncbi.nlm.nih.gov/pubmed/24077661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2629-y
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