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The Mdm2-p53 pathway: multiple roles in kidney development

The molecular basis of nephron progenitor cell renewal and differentiation into nascent epithelial nephrons is an area of intense investigation. Defects in these early stages of nephrogenesis lead to renal hypoplasia, and eventually hypertension and chronic kidney disease. Terminal nephron different...

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Detalhes bibliográficos
Main Authors: El-Dahr, Samir S., Hilliard, Sylvia, Aboudehen, Karam, Saifudeen, Zubaida
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969418/
https://ncbi.nlm.nih.gov/pubmed/24077661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2629-y
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