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A p53-Pax2 Pathway in Kidney Development: Implications for Nephrogenesis

Congenital reduction in nephron number (renal hypoplasia) is a predisposing factor for chronic kidney disease and hypertension. Despite identification of specific genes and pathways in nephrogenesis, determinants of final nephron endowment are poorly understood. Here, we report that mice with germ-l...

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Detalhes bibliográficos
Main Authors: Saifudeen, Zubaida, Liu, Jiao, Dipp, Susana, Yao, Xiao, Li, Yuwen, McLaughlin, Nathaniel, Aboudehen, Karam, El-Dahr, Samir S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440354/
https://ncbi.nlm.nih.gov/pubmed/22984579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044869
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