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p53 Regulates Metanephric Development

p53 is best known as a tumor suppressor that regulates cell-cycle, differentiation, and apoptosis pathways, but its potential role in embryonic development and organogenesis remains controversial. Here, p53(−/−) embryos bred on C57Bl6 background exhibited a spectrum of congenital abnormalities of th...

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Detalhes bibliográficos
Main Authors: Saifudeen, Zubaida, Dipp, Susana, Stefkova, Jana, Yao, Xiao, Lookabaugh, Sarah, El-Dahr, Samir S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799183/
https://ncbi.nlm.nih.gov/pubmed/19729440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008121224
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