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Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase

Identifying direct substrates targeted by protein kinases is important in understanding cellular physiology and intracellular signal transduction. Mass-spectrometry based quantitative proteomics provides a powerful tool for comprehensively characterizing the downstream substrates of protein kinases....

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Wang, Zhihong, Kim, Min-Sik, Ferrando, Isabel Martinez, Koleske, Anthony J., Pandey, Akhilesh, Cole, Philip A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906802/
https://ncbi.nlm.nih.gov/pubmed/29341593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01158
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