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A peptide photoaffinity probe specific for the active conformation of the Abl tyrosine kinase
The design of sensors to monitor the activity state of specific protein kinases is challenging due to the complexity of eukaryotic kinomes. Here we describe a peptide-based photaffinity probe that specifically labels the active conformation of the Abl tyrosine kinase.
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| Hoofdauteurs: | , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595066/ https://ncbi.nlm.nih.gov/pubmed/23081945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200560 |
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