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The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts

Directed cell migration requires precise spatial control of F-actin-based leading edge protrusion, focal adhesion (FA) dynamics, and actomyosin contractility. In spreading fibroblasts, the Abl family kinases, Abl and Arg, primarily localize to the nucleus and cell periphery, respectively. Here we pr...

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Detalhes bibliográficos
Main Authors: Peacock, Justin G., Couch, Brian A., Koleske, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955401/
https://ncbi.nlm.nih.gov/pubmed/20737438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20479
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