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The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts

Directed cell migration requires precise spatial control of F-actin-based leading edge protrusion, focal adhesion (FA) dynamics, and actomyosin contractility. In spreading fibroblasts, the Abl family kinases, Abl and Arg, primarily localize to the nucleus and cell periphery, respectively. Here we pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peacock, Justin G., Couch, Brian A., Koleske, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955401/
https://ncbi.nlm.nih.gov/pubmed/20737438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20479
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