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A peptide photoaffinity probe specific for the active conformation of the Abl tyrosine kinase

The design of sensors to monitor the activity state of specific protein kinases is challenging due to the complexity of eukaryotic kinomes. Here we describe a peptide-based photaffinity probe that specifically labels the active conformation of the Abl tyrosine kinase.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Deng, Yang, Couch, Brian A., Koleske, Anthony J., Turk, Benjamin E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595066/
https://ncbi.nlm.nih.gov/pubmed/23081945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200560
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