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Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase

Identifying direct substrates targeted by protein kinases is important in understanding cellular physiology and intracellular signal transduction. Mass-spectrometry based quantitative proteomics provides a powerful tool for comprehensively characterizing the downstream substrates of protein kinases....

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Wang, Zhihong, Kim, Min-Sik, Ferrando, Isabel Martinez, Koleske, Anthony J., Pandey, Akhilesh, Cole, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906802/
https://ncbi.nlm.nih.gov/pubmed/29341593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01158
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