Llwytho...

Catalytic Diastereo- and Enantioselective Fluoroamination of Alkenes

The stereoselective synthesis of syn-β-fluoroaziridine building blocks via chiral aryl iodide-catalyzed fluorination of allylic amines is reported. The method employs HF-pyridine as a nucleophilic fluoride source together with mCPBA as a stoichiometric oxidant, and affords access to arylethylamine d...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Mennie, Katrina M., Banik, Steven M., Reichert, Elaine C., Jacobsen, Eric N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902804/
https://ncbi.nlm.nih.gov/pubmed/29583001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b02143
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