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Catalytic, Asymmetric Difluorination of Alkenes to Generate Difluoromethylated Stereocenters

Difluoromethyl groups possess specific steric and electronic properties that invite their use as chemically inert surrogates of alcohols, thiols, and other polar functional groups important in a wide assortment of molecular recognition processes. We report here a method for the catalytic, asymmetric...

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Bibliographic Details
Published in:Science
Main Authors: Banik, Steven M., Medley, Jonathan William, Jacobsen, Eric N.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096785/
https://ncbi.nlm.nih.gov/pubmed/27365443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf8078
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