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Catalytic, Asymmetric Difluorination of Alkenes to Generate Difluoromethylated Stereocenters

Difluoromethyl groups possess specific steric and electronic properties that invite their use as chemically inert surrogates of alcohols, thiols, and other polar functional groups important in a wide assortment of molecular recognition processes. We report here a method for the catalytic, asymmetric...

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Bibliografische gegevens
Gepubliceerd in:Science
Hoofdauteurs: Banik, Steven M., Medley, Jonathan William, Jacobsen, Eric N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096785/
https://ncbi.nlm.nih.gov/pubmed/27365443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf8078
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