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Catalytic, Diastereoselective 1,2-Difluorination of Alkenes
We describe a direct, catalytic approach to the 1,2-difluorination of alkenes. The method utilizes a nucleophilic fluoride source and an oxidant in conjunction with an aryl iodide catalyst and is applicable to alkenes with all types of substitution patterns. In general, the vicinal difluoride produc...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5097459/ https://ncbi.nlm.nih.gov/pubmed/27046019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b02391 |
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