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An innovative high-throughput screening approach for discovery of small molecules that inhibit TNF Receptors
Tumor necrosis factor receptor 1 (TNFR1) is a transmembrane receptor that binds tumor necrosis factor or lymphotoxin-alpha and plays a critical role in regulating the inflammatory response. Upregulation of these ligands is associated with inflammatory and autoimmune diseases. Current treatments redu...
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| Publicado en: | SLAS Discov |
|---|---|
| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899890/ https://ncbi.nlm.nih.gov/pubmed/28530838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217706478 |
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