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N-linked glycans are required on epithelial Na(+) channel subunits for maturation and surface expression
Epithelial Na(+) channel (ENaC) subunits undergo N-linked glycosylation in the endoplasmic reticulum where they assemble into an αβγ complex. Six, 13, and 5 consensus sites (Asn-X-Ser/Thr) for N-glycosylation reside in the extracellular domains of the mouse α-, β-, and γ-subunits, respectively. Beca...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899221/ https://ncbi.nlm.nih.gov/pubmed/29187368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00195.2017 |
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