Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum

[Image: see text] Drug resistance has been reported for every antimalarial in use highlighting the need for new strategies to protect the efficacy of therapeutics in development. We have previously shown that resistance can be suppressed with a population biology trap: by identifying situations wher...

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Bibliografiset tiedot
Julkaisussa:ACS Infect Dis
Päätekijät: Ross, Leila Saxby, Lafuente-Monasterio, Maria José, Sakata-Kato, Tomoyo, Mandt, Rebecca E. K., Gamo, Francisco Javier, Wirth, Dyann F., Lukens, Amanda K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2018
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899019/
https://ncbi.nlm.nih.gov/pubmed/29336544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00217
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