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Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum

[Image: see text] Drug resistance has been reported for every antimalarial in use highlighting the need for new strategies to protect the efficacy of therapeutics in development. We have previously shown that resistance can be suppressed with a population biology trap: by identifying situations wher...

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Опубликовано в: :ACS Infect Dis
Главные авторы: Ross, Leila Saxby, Lafuente-Monasterio, Maria José, Sakata-Kato, Tomoyo, Mandt, Rebecca E. K., Gamo, Francisco Javier, Wirth, Dyann F., Lukens, Amanda K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2018
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899019/
https://ncbi.nlm.nih.gov/pubmed/29336544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00217
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