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Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum

[Image: see text] Drug resistance has been reported for every antimalarial in use highlighting the need for new strategies to protect the efficacy of therapeutics in development. We have previously shown that resistance can be suppressed with a population biology trap: by identifying situations wher...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Ross, Leila Saxby, Lafuente-Monasterio, Maria José, Sakata-Kato, Tomoyo, Mandt, Rebecca E. K., Gamo, Francisco Javier, Wirth, Dyann F., Lukens, Amanda K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899019/
https://ncbi.nlm.nih.gov/pubmed/29336544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00217
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