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Sensitivity of adaptive enrichment trial designs to accrual rates, time to outcome measurement, and prognostic variables

Adaptive enrichment designs involve rules for restricting enrollment to a subset of the population during the course of an ongoing trial. This can be used to target those who benefit from the experimental treatment. Trial characteristics such as the accrual rate and the prognostic value of baseline...

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Bibliografske podrobnosti
izdano v:Contemp Clin Trials Commun
Main Authors: Qian, Tianchen, Colantuoni, Elizabeth, Fisher, Aaron, Rosenblum, Michael
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898543/
https://ncbi.nlm.nih.gov/pubmed/29696195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2017.08.003
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