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Auxiliary-variable-enriched Biomarker-Stratified Design

Clinical trials in the era of precision medicine require assessment of biomarkers to identify appropriate subgroups of patients for targeted therapy. In a biomarker-stratified design (BSD), biomarkers are measured on all patients and used as stratification variables. However, such a trial can be bot...

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Bibliografiska uppgifter
I publikationen:Stat Med
Huvudupphovsmän: Wang, Ting, Wang, Xiaofei, Zhou, Haibo, Cai, Jianwen, George, Stephen L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279614/
https://ncbi.nlm.nih.gov/pubmed/30221368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7938
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