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Sensitivity of adaptive enrichment trial designs to accrual rates, time to outcome measurement, and prognostic variables

Adaptive enrichment designs involve rules for restricting enrollment to a subset of the population during the course of an ongoing trial. This can be used to target those who benefit from the experimental treatment. Trial characteristics such as the accrual rate and the prognostic value of baseline...

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Библиографические подробности
Опубликовано в: :Contemp Clin Trials Commun
Главные авторы: Qian, Tianchen, Colantuoni, Elizabeth, Fisher, Aaron, Rosenblum, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898543/
https://ncbi.nlm.nih.gov/pubmed/29696195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2017.08.003
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