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Building Efficient Comparative Effectiveness Trials through Adaptive Designs, Utility Functions, and Accrual Rate Optimization: Finding the Sweet Spot
The time is right for the use of Bayesian Adaptive Designs (BAD) in comparative effectiveness trials. For example, PCORI has joined the FDA and NIH in adopting policies/guidelines encouraging their use. There are multiple aspects to BAD that need to be considered when designing a comparative effecti...
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| Publicado no: | Stat Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355191/ https://ncbi.nlm.nih.gov/pubmed/25640114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6403 |
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