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Adaptive enrichment designs for clinical trials
Modern medicine has graduated from broad spectrum treatments to targeted therapeutics. New drugs recognize the recently discovered heterogeneity of many diseases previously considered to be fairly homogeneous. These treatments attack specific genetic pathways which are only dysregulated in some smal...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769998/ https://ncbi.nlm.nih.gov/pubmed/23525452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxt010 |
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